Motif ID: POU5F1_SOX2{dimer}.p2

Z-value: 1.281


Transcription factors associated with POU5F1_SOX2{dimer}.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1
SOX2 6657 SRY (sex determining region Y)-box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_31242593-0.292.7e-01Click!
SOX2chr3_+_1829127690.136.3e-01Click!


Activity profile for motif POU5F1_SOX2{dimer}.p2.

activity profile for motif POU5F1_SOX2{dimer}.p2


Sorted Z-values histogram for motif POU5F1_SOX2{dimer}.p2

Sorted Z-values for motif POU5F1_SOX2{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1_SOX2{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_100714995 1.100 MTTP
microsomal triglyceride transfer protein
chr5_+_27508139 1.067 LOC643401
hypothetical protein LOC643401
chr10_+_7785235 0.967 NM_002216
 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785290 0.966 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785331 0.956 ITIH2
inter-alpha (globulin) inhibitor H2
chr17_+_24394281 0.956 PIPOX
pipecolic acid oxidase
chr10_+_7785360 0.947 ITIH2
inter-alpha (globulin) inhibitor H2
chr8_-_17797127 0.904 NM_147203
NM_201553
NM_004467
NM_201552
 FGL1



fibrinogen-like 1



chr11_-_117552545 0.873 NM_004588
 SCN2B
sodium channel, voltage-gated, type II, beta
chr12_-_7547552 0.859 NM_004244
NM_203416
 CD163

CD163 molecule

chr16_-_54424517 0.830 NM_001025194
NM_001025195
NM_001266
 CES1


carboxylesterase 1


chr6_+_32515596 0.818 NM_019111
 HLA-DRA
major histocompatibility complex, class II, DR alpha
chr3_-_156904690 0.805 NM_014996
 PLCH1
phospholipase C, eta 1
chr4_+_74493174 0.799 ALB
albumin
chr2_+_36777336 0.741 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
 VIT




vitrin




chr12_+_7755316 0.734 NM_199286
 DPPA3
STELLAR
developmental pluripotency associated 3
developmental pluripotency associated 3 pseudogene
chr4_+_74493918 0.714 ALB
albumin
chr1_+_61315516 0.709 NM_001145511
 NFIA
nuclear factor I/A
chr20_+_16312 0.705 NM_153325
 DEFB125
defensin, beta 125
chr17_+_24394043 0.701 NM_016518
 PIPOX
pipecolic acid oxidase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
6.67 6.75e-04 GO:0031214 biomineral tissue development
6.11 1.93e-05 GO:0072376 protein activation cascade
3.24 1.29e-10 GO:0007608 sensory perception of smell
3.19 1.57e-11 GO:0007606 sensory perception of chemical stimulus
2.26 2.07e-07 GO:0007600 sensory perception
1.95 2.90e-03 GO:0006955 immune response
1.79 6.44e-05 GO:0050877 neurological system process
1.66 2.25e-04 GO:0003008 system process
1.37 5.04e-09 GO:0050896 response to stimulus
1.32 1.56e-04 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.78 5.35e-03 GO:0005615 extracellular space
1.69 1.15e-07 GO:0005576 extracellular region
1.66 8.02e-03 GO:0044421 extracellular region part
1.41 6.34e-07 GO:0071944 cell periphery
1.41 8.14e-07 GO:0005886 plasma membrane
1.25 2.15e-03 GO:0031224 intrinsic to membrane
1.24 2.93e-03 GO:0016021 integral to membrane
1.20 1.10e-02 GO:0044425 membrane part
1.15 3.83e-02 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
3.33 1.88e-11 GO:0004984 olfactory receptor activity
2.65 4.09e-14 GO:0004930 G-protein coupled receptor activity
2.36 9.41e-16 GO:0004888 transmembrane receptor activity
1.98 9.09e-12 GO:0004872 receptor activity
1.77 1.92e-09 GO:0004871 signal transducer activity
1.77 1.92e-09 GO:0060089 molecular transducer activity